Deletion of the Caenorhabditis elegans homologues of the CLN3 gene, involved in human juvenile neuronal ceroid lipofuscinosis, causes a mild progeric phenotype. [electronic resource]
Producer: 20060705Description: 1065-80 p. digitalISSN:- 0141-8955
- Alleles
- Animals
- Caenorhabditis elegans
- Carbohydrate Metabolism
- Cosmids
- DNA Primers
- Disease Models, Animal
- Female
- Gene Deletion
- Genes, Reporter
- Green Fluorescent Proteins -- metabolism
- Lysosomes -- metabolism
- Male
- Membrane Glycoproteins -- metabolism
- Microscopy, Electron
- Microscopy, Fluorescence
- Models, Genetic
- Models, Statistical
- Molecular Chaperones -- metabolism
- Mutation
- Mutation, Missense
- Neurodegenerative Diseases
- Neuronal Ceroid-Lipofuscinoses -- diagnosis
- Neurons -- metabolism
- Phenotype
- Progeria -- genetics
- Promoter Regions, Genetic
- Recombinant Fusion Proteins -- metabolism
- Time Factors
- Transgenes
No physical items for this record
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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