Deletion of the Caenorhabditis elegans homologues of the CLN3 gene, involved in human juvenile neuronal ceroid lipofuscinosis, causes a mild progeric phenotype.

de Voer, G

Deletion of the Caenorhabditis elegans homologues of the CLN3 gene, involved in human juvenile neuronal ceroid lipofuscinosis, causes a mild progeric phenotype. [electronic resource] - Journal of inherited metabolic disease 2005 - 1065-80 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

0141-8955

10.1007/s10545-005-0125-7 doi


Alleles
Animals
Caenorhabditis elegans
Carbohydrate Metabolism
Cosmids
DNA Primers
Disease Models, Animal
Female
Gene Deletion
Genes, Reporter
Green Fluorescent Proteins--metabolism
Lysosomes--metabolism
Male
Membrane Glycoproteins--metabolism
Microscopy, Electron
Microscopy, Fluorescence
Models, Genetic
Models, Statistical
Molecular Chaperones--metabolism
Mutation
Mutation, Missense
Neurodegenerative Diseases
Neuronal Ceroid-Lipofuscinoses--diagnosis
Neurons--metabolism
Phenotype
Progeria--genetics
Promoter Regions, Genetic
Recombinant Fusion Proteins--metabolism
Time Factors
Transgenes