Pharmacokinetics and pharmacodynamics of the vasopeptidase inhibitor AVE7688 in humans. [electronic resource]
Producer: 20060208Description: 49-61 p. digitalISSN:- 0009-9236
- Adolescent
- Adult
- Aldosterone -- urine
- Angiotensin II Type 1 Receptor Blockers -- pharmacology
- Angiotensin-Converting Enzyme Inhibitors -- pharmacokinetics
- Atrial Natriuretic Factor -- urine
- Biotransformation
- Biphenyl Compounds -- pharmacology
- Cross-Over Studies
- Cyclic GMP -- urine
- Dose-Response Relationship, Drug
- Heterocyclic Compounds, 3-Ring -- pharmacokinetics
- Humans
- Irbesartan
- Male
- Natriuresis -- drug effects
- Oligopeptides -- urine
- Peptidyl-Dipeptidase A -- blood
- Protease Inhibitors -- pharmacokinetics
- Ramipril -- pharmacology
- Renin -- blood
- Renin-Angiotensin System -- drug effects
- Single-Blind Method
- Tetrazoles -- pharmacology
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Publication Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
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