The tumor suppressor PTEN is necessary for human Sprouty 2-mediated inhibition of cell proliferation. [electronic resource]
Producer: 20060504Description: 4816-22 p. digitalISSN:- 0021-9258
- Adaptor Proteins, Signal Transducing
- Animals
- Blotting, Western
- Cell Cycle
- Cell Proliferation
- Cells, Cultured
- Cytosol -- metabolism
- DNA Primers -- chemistry
- Epidermal Growth Factor -- metabolism
- Fibroblasts -- metabolism
- G1 Phase
- HeLa Cells
- Humans
- Intracellular Signaling Peptides and Proteins
- Membrane Proteins
- Mice
- Mice, Transgenic
- PTEN Phosphohydrolase -- metabolism
- Phosphorylation
- Plasmids -- metabolism
- Protein Serine-Threonine Kinases
- Proteins -- metabolism
- Proto-Oncogene Proteins c-akt -- metabolism
- RNA, Small Interfering -- metabolism
- Reverse Transcriptase Polymerase Chain Reaction
- S Phase
- Static Electricity
- Thymidine -- chemistry
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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