The tumor suppressor PTEN is necessary for human Sprouty 2-mediated inhibition of cell proliferation.

Edwin, Francis

The tumor suppressor PTEN is necessary for human Sprouty 2-mediated inhibition of cell proliferation. [electronic resource] - The Journal of biological chemistry Feb 2006 - 4816-22 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

0021-9258

10.1074/jbc.M508300200 doi


Adaptor Proteins, Signal Transducing
Animals
Blotting, Western
Cell Cycle
Cell Proliferation
Cells, Cultured
Cytosol--metabolism
DNA Primers--chemistry
Epidermal Growth Factor--metabolism
Fibroblasts--metabolism
G1 Phase
HeLa Cells
Humans
Intracellular Signaling Peptides and Proteins
Membrane Proteins
Mice
Mice, Transgenic
PTEN Phosphohydrolase--metabolism
Phosphorylation
Plasmids--metabolism
Protein Serine-Threonine Kinases
Proteins--metabolism
Proto-Oncogene Proteins c-akt--metabolism
RNA, Small Interfering--metabolism
Reverse Transcriptase Polymerase Chain Reaction
S Phase
Static Electricity
Thymidine--chemistry