Depletion of securin increases arsenite-induced chromosome instability and apoptosis via a p53-independent pathway. [electronic resource]
Producer: 20060330Description: 73-86 p. digitalISSN:- 1096-6080
- Animals
- Apoptosis -- drug effects
- Arsenites -- toxicity
- CDC2 Protein Kinase -- antagonists & inhibitors
- Carrier Proteins -- metabolism
- Cell Line, Tumor
- Cell Survival -- drug effects
- Colorectal Neoplasms -- drug therapy
- Cyclin B -- metabolism
- Cyclin B1
- Dose-Response Relationship, Drug
- Endothelium, Vascular -- drug effects
- Enzyme Inhibitors -- toxicity
- Epithelial Cells -- drug effects
- Mice
- Mitosis -- drug effects
- Securin
- Sister Chromatid Exchange -- drug effects
- Sodium Compounds -- toxicity
- Tumor Suppressor Protein p53 -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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