Macrocyclic peptidomimetic inhibitors of beta-secretase (BACE): first X-ray structure of a macrocyclic peptidomimetic-BACE complex. [electronic resource]
Producer: 20060321Description: 191-5 p. digitalISSN:- 0960-894X
- Alzheimer Disease -- drug therapy
- Amyloid Precursor Protein Secretases
- Amyloid beta-Protein Precursor -- chemistry
- Animals
- Aspartic Acid Endopeptidases
- Cell Line
- Chemistry, Pharmaceutical -- methods
- Crystallography, X-Ray -- methods
- Drug Design
- Endopeptidases -- chemistry
- Humans
- Kinetics
- Models, Chemical
- Models, Molecular
- Protein Conformation
- Protein Structure, Tertiary
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Publication Type: Journal Article
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