Bepridil, an antiarrhythmic drug, opens mitochondrial KATP channels, blocks sarcolemmal KATP channels, and confers cardioprotection. [electronic resource]
Producer: 20060331Description: 182-8 p. digitalISSN:- 0022-3565
- Algorithms
- Animals
- Anti-Arrhythmia Agents -- pharmacology
- Bepridil -- pharmacology
- Cell Line
- Cell Separation
- Coronary Circulation
- Flavoproteins -- metabolism
- Fluorescence
- Guinea Pigs
- Heart Diseases -- prevention & control
- Heart Ventricles -- metabolism
- Humans
- In Vitro Techniques
- Kidney -- drug effects
- Mitochondria -- drug effects
- Myocytes, Cardiac -- drug effects
- Potassium Channel Blockers
- Potassium Channels -- agonists
- Sarcolemma -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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