Bepridil, an antiarrhythmic drug, opens mitochondrial KATP channels, blocks sarcolemmal KATP channels, and confers cardioprotection.

Sato, Toshiaki

Bepridil, an antiarrhythmic drug, opens mitochondrial KATP channels, blocks sarcolemmal KATP channels, and confers cardioprotection. [electronic resource] - The Journal of pharmacology and experimental therapeutics Jan 2006 - 182-8 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0022-3565

10.1124/jpet.105.094029 doi


Algorithms
Animals
Anti-Arrhythmia Agents--pharmacology
Bepridil--pharmacology
Cell Line
Cell Separation
Coronary Circulation
Flavoproteins--metabolism
Fluorescence
Guinea Pigs
Heart Diseases--prevention & control
Heart Ventricles--metabolism
Humans
In Vitro Techniques
Kidney--drug effects
Mitochondria--drug effects
Myocytes, Cardiac--drug effects
Potassium Channel Blockers
Potassium Channels--agonists
Sarcolemma--drug effects