Tumor necrosis factor (TNF) alpha increases collagen accumulation and proliferation in intestinal myofibroblasts via TNF receptor 2. [electronic resource]
Producer: 20060104Description: 36099-109 p. digitalISSN:- 0021-9258
- Animals
- Blotting, Northern
- Blotting, Western
- Cell Proliferation
- Collagen -- metabolism
- DNA -- chemistry
- Dose-Response Relationship, Drug
- Enzyme Activation
- Fibroblasts -- metabolism
- Fibrosis -- metabolism
- Genotype
- Green Fluorescent Proteins -- metabolism
- Homozygote
- Inflammation
- Insulin-Like Growth Factor I -- metabolism
- Intestinal Mucosa -- metabolism
- Matrix Metalloproteinase 2 -- metabolism
- Mice
- Mice, Transgenic
- Mitogen-Activated Protein Kinase 1 -- metabolism
- Mitogen-Activated Protein Kinase 3 -- metabolism
- NF-kappa B -- metabolism
- Protein Isoforms
- RNA -- metabolism
- RNA, Messenger -- metabolism
- Receptors, Tumor Necrosis Factor -- chemistry
- Receptors, Tumor Necrosis Factor, Type II -- metabolism
- STAT3 Transcription Factor -- metabolism
- Signal Transduction
- Time Factors
- Tissue Inhibitor of Metalloproteinase-1 -- metabolism
- Transcription Factor AP-1 -- metabolism
- Transcription, Genetic
- Transcriptional Activation
- Tumor Necrosis Factor-alpha -- metabolism
- Up-Regulation
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
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