Tumor necrosis factor (TNF) alpha increases collagen accumulation and proliferation in intestinal myofibroblasts via TNF receptor 2.

Theiss, Arianne L

Tumor necrosis factor (TNF) alpha increases collagen accumulation and proliferation in intestinal myofibroblasts via TNF receptor 2. [electronic resource] - The Journal of biological chemistry Oct 2005 - 36099-109 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.

0021-9258

10.1074/jbc.M505291200 doi


Animals
Blotting, Northern
Blotting, Western
Cell Proliferation
Collagen--metabolism
DNA--chemistry
Dose-Response Relationship, Drug
Enzyme Activation
Fibroblasts--metabolism
Fibrosis--metabolism
Genotype
Green Fluorescent Proteins--metabolism
Homozygote
Inflammation
Insulin-Like Growth Factor I--metabolism
Intestinal Mucosa--metabolism
Matrix Metalloproteinase 2--metabolism
Mice
Mice, Transgenic
Mitogen-Activated Protein Kinase 1--metabolism
Mitogen-Activated Protein Kinase 3--metabolism
NF-kappa B--metabolism
Protein Isoforms
RNA--metabolism
RNA, Messenger--metabolism
Receptors, Tumor Necrosis Factor--chemistry
Receptors, Tumor Necrosis Factor, Type II--metabolism
STAT3 Transcription Factor--metabolism
Signal Transduction
Time Factors
Tissue Inhibitor of Metalloproteinase-1--metabolism
Transcription Factor AP-1--metabolism
Transcription, Genetic
Transcriptional Activation
Tumor Necrosis Factor-alpha--metabolism
Up-Regulation