Hydroxyurea enhances SMN2 gene expression in spinal muscular atrophy cells. [electronic resource]
Producer: 20051031Description: 194-202 p. digitalISSN:- 0364-5134
- Blotting, Western
- Cyclic AMP Response Element-Binding Protein -- genetics
- Dose-Response Relationship, Drug
- Enzyme Inhibitors -- pharmacology
- Gene Dosage
- Gene Expression -- drug effects
- Gene Expression Regulation -- drug effects
- Humans
- Hydroxyurea -- pharmacology
- Immunohistochemistry -- methods
- Lymphocytes -- drug effects
- Motor Neurons -- drug effects
- Muscular Atrophy, Spinal -- classification
- Nerve Tissue Proteins -- genetics
- RNA, Messenger -- metabolism
- RNA-Binding Proteins -- genetics
- Reverse Transcriptase Polymerase Chain Reaction -- methods
- SMN Complex Proteins
- Survival of Motor Neuron 1 Protein
- Survival of Motor Neuron 2 Protein
- Time Factors
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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