Hepatic gene expression changes in mouse models with liver-specific deletion or global suppression of the NADPH-cytochrome P450 reductase gene. Mechanistic implications for the regulation of microsomal cytochrome P450 and the fatty liver phenotype. [electronic resource]
Producer: 20051108Description: 31686-98 p. digitalISSN:- 0021-9258
- Animals
- Cholesterol -- biosynthesis
- Cytochrome P-450 Enzyme System -- metabolism
- Enzyme Repression
- Fatty Acids -- biosynthesis
- Fatty Liver -- enzymology
- Gene Deletion
- Gene Expression Profiling
- Mice
- Mice, Knockout
- Microsomes, Liver -- enzymology
- NADPH-Ferrihemoprotein Reductase -- biosynthesis
- Oligonucleotide Array Sequence Analysis
- Phenotype
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
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