DNA-protein cross-links and replication-dependent histone H2AX phosphorylation induced by aminoflavone (NSC 686288), a novel anticancer agent active against human breast cancer cells. [electronic resource]
Producer: 20050808Description: 5337-43 p. digitalISSN:- 0008-5472
- Breast Neoplasms -- drug therapy
- Cell Cycle Proteins -- biosynthesis
- Cell Line, Tumor
- Cross-Linking Reagents -- pharmacology
- Cyclin-Dependent Kinase Inhibitor p21
- DNA Damage
- DNA Replication -- drug effects
- DNA, Neoplasm -- drug effects
- DNA, Single-Stranded -- drug effects
- DNA-Binding Proteins -- metabolism
- Flavonoids -- pharmacology
- Histones -- metabolism
- Humans
- Nuclear Proteins -- biosynthesis
- Phosphorylation -- drug effects
- Proto-Oncogene Proteins -- biosynthesis
- Proto-Oncogene Proteins c-mdm2
- Replication Protein A
- S Phase -- drug effects
- Tumor Suppressor Protein p53 -- metabolism
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Publication Type: Journal Article
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