DNA-protein cross-links and replication-dependent histone H2AX phosphorylation induced by aminoflavone (NSC 686288), a novel anticancer agent active against human breast cancer cells.
Meng, Ling-hua
DNA-protein cross-links and replication-dependent histone H2AX phosphorylation induced by aminoflavone (NSC 686288), a novel anticancer agent active against human breast cancer cells. [electronic resource] - Cancer research Jun 2005 - 5337-43 p. digital
Publication Type: Journal Article
0008-5472
10.1158/0008-5472.CAN-05-0003 doi
Breast Neoplasms--drug therapy
Cell Cycle Proteins--biosynthesis
Cell Line, Tumor
Cross-Linking Reagents--pharmacology
Cyclin-Dependent Kinase Inhibitor p21
DNA Damage
DNA Replication--drug effects
DNA, Neoplasm--drug effects
DNA, Single-Stranded--drug effects
DNA-Binding Proteins--metabolism
Flavonoids--pharmacology
Histones--metabolism
Humans
Nuclear Proteins--biosynthesis
Phosphorylation--drug effects
Proto-Oncogene Proteins--biosynthesis
Proto-Oncogene Proteins c-mdm2
Replication Protein A
S Phase--drug effects
Tumor Suppressor Protein p53--metabolism
DNA-protein cross-links and replication-dependent histone H2AX phosphorylation induced by aminoflavone (NSC 686288), a novel anticancer agent active against human breast cancer cells. [electronic resource] - Cancer research Jun 2005 - 5337-43 p. digital
Publication Type: Journal Article
0008-5472
10.1158/0008-5472.CAN-05-0003 doi
Breast Neoplasms--drug therapy
Cell Cycle Proteins--biosynthesis
Cell Line, Tumor
Cross-Linking Reagents--pharmacology
Cyclin-Dependent Kinase Inhibitor p21
DNA Damage
DNA Replication--drug effects
DNA, Neoplasm--drug effects
DNA, Single-Stranded--drug effects
DNA-Binding Proteins--metabolism
Flavonoids--pharmacology
Histones--metabolism
Humans
Nuclear Proteins--biosynthesis
Phosphorylation--drug effects
Proto-Oncogene Proteins--biosynthesis
Proto-Oncogene Proteins c-mdm2
Replication Protein A
S Phase--drug effects
Tumor Suppressor Protein p53--metabolism