Role of PI3K/Akt and MEK/ERK signaling pathways in sulforaphane- and erucin-induced phase II enzymes and MRP2 transcription, G2/M arrest and cell death in Caco-2 cells. [electronic resource]
Producer: 20050708Description: 1543-52 p. digitalISSN:- 0006-2952
- Caco-2 Cells
- Cell Death -- drug effects
- Cell Division -- drug effects
- Enzyme Induction -- drug effects
- Enzyme Inhibitors -- pharmacology
- Extracellular Signal-Regulated MAP Kinases -- physiology
- G2 Phase -- drug effects
- Glucuronosyltransferase -- biosynthesis
- Humans
- Isothiocyanates
- MAP Kinase Kinase Kinases -- physiology
- MAP Kinase Signaling System -- drug effects
- Membrane Transport Proteins -- genetics
- Multidrug Resistance-Associated Protein 2
- Multidrug Resistance-Associated Proteins -- genetics
- NAD(P)H Dehydrogenase (Quinone) -- biosynthesis
- Phosphatidylinositol 3-Kinases -- physiology
- Protein Serine-Threonine Kinases -- physiology
- Proto-Oncogene Proteins -- physiology
- Proto-Oncogene Proteins c-akt
- Sulfides -- pharmacology
- Sulfoxides
- Thiocyanates -- pharmacology
- Transcription, Genetic -- drug effects
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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