Disruption of fibroblast growth factor signal pathway inhibits the growth of synovial sarcomas: potential application of signal inhibitors to molecular target therapy. [electronic resource]
Producer: 20050808Description: 2702-12 p. digitalISSN:- 1078-0432
- Animals
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Dose-Response Relationship, Drug
- Enzyme Activation -- drug effects
- Female
- Fibroblast Growth Factors -- genetics
- Gene Expression Regulation, Neoplastic
- Humans
- Male
- Mice
- Mice, Inbred BALB C
- Mice, Nude
- Mitogen-Activated Protein Kinase 1 -- metabolism
- Mitogen-Activated Protein Kinase 3 -- metabolism
- Mitogen-Activated Protein Kinases -- metabolism
- Phosphorylation -- drug effects
- Protein Isoforms -- genetics
- Pyrimidines -- pharmacology
- Pyrroles -- pharmacology
- RNA, Messenger -- genetics
- Receptors, Fibroblast Growth Factor -- antagonists & inhibitors
- Recombinant Proteins -- pharmacology
- Reverse Transcriptase Polymerase Chain Reaction
- Sarcoma, Synovial -- genetics
- Signal Transduction -- drug effects
- Urea -- analogs & derivatives
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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