An MDR1-3435 variant is associated with higher plasma nelfinavir levels and more rapid virologic response in HIV-1 infected children. [electronic resource]
Producer: 20050503Description: 371-80 p. digitalISSN:- 0269-9370
- Antiretroviral Therapy, Highly Active
- CD4 Lymphocyte Count
- Child
- Child, Preschool
- Cytochrome P-450 Enzyme System -- genetics
- Female
- Genes, MDR -- genetics
- Genotype
- HIV Infections -- blood
- HIV Protease Inhibitors -- blood
- HIV-1 -- isolation & purification
- Humans
- Male
- Nelfinavir -- blood
- Polymorphism, Single Nucleotide
- RNA, Viral -- blood
- Treatment Outcome
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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