An MDR1-3435 variant is associated with higher plasma nelfinavir levels and more rapid virologic response in HIV-1 infected children.
Saitoh, Akihiko
An MDR1-3435 variant is associated with higher plasma nelfinavir levels and more rapid virologic response in HIV-1 infected children. [electronic resource] - AIDS (London, England) Mar 2005 - 371-80 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0269-9370
10.1097/01.aids.0000161766.13782.2f doi
Antiretroviral Therapy, Highly Active
CD4 Lymphocyte Count
Child
Child, Preschool
Cytochrome P-450 Enzyme System--genetics
Female
Genes, MDR--genetics
Genotype
HIV Infections--blood
HIV Protease Inhibitors--blood
HIV-1--isolation & purification
Humans
Male
Nelfinavir--blood
Polymorphism, Single Nucleotide
RNA, Viral--blood
Treatment Outcome
An MDR1-3435 variant is associated with higher plasma nelfinavir levels and more rapid virologic response in HIV-1 infected children. [electronic resource] - AIDS (London, England) Mar 2005 - 371-80 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0269-9370
10.1097/01.aids.0000161766.13782.2f doi
Antiretroviral Therapy, Highly Active
CD4 Lymphocyte Count
Child
Child, Preschool
Cytochrome P-450 Enzyme System--genetics
Female
Genes, MDR--genetics
Genotype
HIV Infections--blood
HIV Protease Inhibitors--blood
HIV-1--isolation & purification
Humans
Male
Nelfinavir--blood
Polymorphism, Single Nucleotide
RNA, Viral--blood
Treatment Outcome