FLT3-ITD and tyrosine kinase domain mutants induce 2 distinct phenotypes in a murine bone marrow transplantation model. [electronic resource]
Producer: 20050713Description: 4792-9 p. digitalISSN:- 0006-4971
- Animals
- Blotting, Southern
- Bone Marrow Cells -- cytology
- Bone Marrow Transplantation
- Cell Separation
- DNA, Complementary -- metabolism
- DNA-Binding Proteins -- metabolism
- Flow Cytometry
- Green Fluorescent Proteins -- metabolism
- Immunoblotting
- Immunophenotyping
- Immunoprecipitation
- Leukemia, Myeloid, Acute -- genetics
- Mice
- Milk Proteins -- metabolism
- Mutation
- Myeloproliferative Disorders -- genetics
- Phenotype
- Point Mutation
- Precursor Cell Lymphoblastic Leukemia-Lymphoma -- genetics
- Protein Structure, Tertiary
- Protein-Tyrosine Kinases -- chemistry
- Proto-Oncogene Proteins -- chemistry
- Receptor Protein-Tyrosine Kinases -- chemistry
- Recombinant Proteins -- chemistry
- Retroviridae -- genetics
- STAT5 Transcription Factor
- Signal Transduction
- Splenomegaly -- pathology
- Trans-Activators -- metabolism
- Treatment Outcome
- fms-Like Tyrosine Kinase 3
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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