Role of the interactions between the active site base and the substrate Schiff base in amine oxidase catalysis. Evidence from structural and spectroscopic studies of the 2-hydrazinopyridine adduct of Escherichia coli amine oxidase. [electronic resource]
Producer: 20050607Description: 1568-82 p. digitalISSN:- 0006-2960
- Amine Oxidase (Copper-Containing) -- antagonists & inhibitors
- Binding Sites -- genetics
- Catalysis
- Crystallography, X-Ray
- Enzyme Inhibitors -- chemistry
- Enzyme Stability -- genetics
- Escherichia coli Proteins -- antagonists & inhibitors
- Hydrogen-Ion Concentration
- Kinetics
- Mutagenesis, Site-Directed
- Nuclear Magnetic Resonance, Biomolecular
- Pyridones -- chemistry
- Schiff Bases -- metabolism
- Solutions
- Spectrophotometry, Ultraviolet
- Spectrum Analysis, Raman
- Substrate Specificity -- genetics
- Titrimetry
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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