Possible involvement of pregnane X receptor-enhanced CYP24 expression in drug-induced osteomalacia. [electronic resource]
Producer: 20050210Description: 177-86 p. digitalISSN:- 0021-9738
- Animals
- Cells, Cultured
- Cytochrome P-450 Enzyme System -- biosynthesis
- Gene Expression Regulation -- drug effects
- Hepatocytes -- drug effects
- Humans
- Mice
- Molecular Sequence Data
- Mutation -- genetics
- Osteomalacia -- chemically induced
- Pregnane X Receptor
- Promoter Regions, Genetic -- genetics
- RNA, Messenger -- genetics
- Receptors, Cytoplasmic and Nuclear -- agonists
- Receptors, Steroid -- agonists
- Rifampin -- pharmacology
- Steroid Hydroxylases -- biosynthesis
- Transcriptional Activation -- genetics
- Vitamin D Response Element -- genetics
- Vitamin D3 24-Hydroxylase
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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