Chronic hyperalgesic priming in the rat involves a novel interaction between cAMP and PKCepsilon second messenger pathways. [electronic resource]
Producer: 20050418Description: 185-90 p. digitalISSN:- 0304-3959
- 8-Bromo Cyclic Adenosine Monophosphate -- toxicity
- Analysis of Variance
- Animals
- Behavior, Animal -- drug effects
- Carrageenan
- Colforsin -- toxicity
- Cyclic AMP -- antagonists & inhibitors
- Cyclic GMP -- analogs & derivatives
- Dinoprostone -- toxicity
- Disease Models, Animal
- Dose-Response Relationship, Drug
- Drug Interactions
- Enzyme Inhibitors -- pharmacology
- Hyperalgesia -- chemically induced
- Male
- Models, Biological
- Pain Measurement -- methods
- Pain Threshold -- drug effects
- Protein Kinase C -- antagonists & inhibitors
- Protein Kinase C-epsilon
- Rats
- Rats, Sprague-Dawley
- Second Messenger Systems -- physiology
- Thionucleotides -- toxicity
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Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
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