Chronic hyperalgesic priming in the rat involves a novel interaction between cAMP and PKCepsilon second messenger pathways.

Parada, C A

Chronic hyperalgesic priming in the rat involves a novel interaction between cAMP and PKCepsilon second messenger pathways. [electronic resource] - Pain Jan 2005 - 185-90 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.

0304-3959

10.1016/j.pain.2004.10.021 doi


8-Bromo Cyclic Adenosine Monophosphate--toxicity
Analysis of Variance
Animals
Behavior, Animal--drug effects
Carrageenan
Colforsin--toxicity
Cyclic AMP--antagonists & inhibitors
Cyclic GMP--analogs & derivatives
Dinoprostone--toxicity
Disease Models, Animal
Dose-Response Relationship, Drug
Drug Interactions
Enzyme Inhibitors--pharmacology
Hyperalgesia--chemically induced
Male
Models, Biological
Pain Measurement--methods
Pain Threshold--drug effects
Protein Kinase C--antagonists & inhibitors
Protein Kinase C-epsilon
Rats
Rats, Sprague-Dawley
Second Messenger Systems--physiology
Thionucleotides--toxicity