Functional overexpression of gamma-secretase reveals protease-independent trafficking functions and a critical role of lipids for protease activity. [electronic resource]
Producer: 20050513Description: 12523-35 p. digitalISSN:- 0021-9258
- Amyloid Precursor Protein Secretases
- Amyloid beta-Protein Precursor -- metabolism
- Aspartic Acid Endopeptidases
- Binding Sites
- Blotting, Western
- Brain -- metabolism
- Catalysis
- Cell Line
- Cell Membrane -- metabolism
- Cell-Free System -- metabolism
- Chromatography
- Culture Media -- metabolism
- Culture Media, Conditioned -- pharmacology
- DNA, Complementary -- metabolism
- Dimerization
- Endopeptidases -- biosynthesis
- Golgi Apparatus -- metabolism
- Humans
- Immunohistochemistry
- Lipid Metabolism
- Membrane Glycoproteins -- metabolism
- Peptide Hydrolases -- metabolism
- Peptides -- chemistry
- Protein Structure, Tertiary
- Time Factors
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Publication Type: Journal Article
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