Macrolactamization of glycosylated peptide thioesters by the thioesterase domain of tyrocidine synthetase. [electronic resource]
Producer: 20050714Description: 1635-42 p. digitalISSN:- 1074-5521
- Bacillus subtilis -- drug effects
- Catalytic Domain
- Cyclization
- Drug Evaluation, Preclinical
- Erythrocytes -- drug effects
- Esters -- chemical synthesis
- Glycosylation
- Humans
- Kinetics
- Lactams -- chemical synthesis
- Macrocyclic Compounds -- chemical synthesis
- Molecular Conformation
- Peptide Synthases -- chemistry
- Peptides -- chemical synthesis
- Substrate Specificity
- Thiolester Hydrolases -- chemistry
- Tyrocidine -- analogs & derivatives
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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