Macrolactamization of glycosylated peptide thioesters by the thioesterase domain of tyrocidine synthetase.

Lin, Hening

Macrolactamization of glycosylated peptide thioesters by the thioesterase domain of tyrocidine synthetase. [electronic resource] - Chemistry & biology Dec 2004 - 1635-42 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

1074-5521

10.1016/j.chembiol.2004.09.015 doi


Bacillus subtilis--drug effects
Catalytic Domain
Cyclization
Drug Evaluation, Preclinical
Erythrocytes--drug effects
Esters--chemical synthesis
Glycosylation
Humans
Kinetics
Lactams--chemical synthesis
Macrocyclic Compounds--chemical synthesis
Molecular Conformation
Peptide Synthases--chemistry
Peptides--chemical synthesis
Substrate Specificity
Thiolester Hydrolases--chemistry
Tyrocidine--analogs & derivatives