In vitro zonation and toxicity in a hepatocyte bioreactor. [electronic resource]
Producer: 20050608Description: 110-9 p. digitalISSN:- 1096-6080
- Acetaminophen -- toxicity
- Algorithms
- Analgesics, Non-Narcotic -- toxicity
- Animals
- Aryl Hydrocarbon Hydroxylases -- metabolism
- Bioreactors
- Blotting, Western
- Cell Separation
- Cell Survival -- drug effects
- Coculture Techniques
- Cytochrome P-450 CYP2B1 -- metabolism
- Cytochrome P-450 CYP3A
- Female
- Fibroblasts -- drug effects
- Hepatocytes -- drug effects
- Image Processing, Computer-Assisted
- Liver -- drug effects
- Models, Statistical
- Oxidoreductases, N-Demethylating -- metabolism
- Oxygen Consumption -- physiology
- Rats
- Rats, Inbred Lew
- Toxicity Tests
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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