In vitro zonation and toxicity in a hepatocyte bioreactor.

Allen, Jared W

In vitro zonation and toxicity in a hepatocyte bioreactor. [electronic resource] - Toxicological sciences : an official journal of the Society of Toxicology Mar 2005 - 110-9 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

1096-6080

10.1093/toxsci/kfi052 doi


Acetaminophen--toxicity
Algorithms
Analgesics, Non-Narcotic--toxicity
Animals
Aryl Hydrocarbon Hydroxylases--metabolism
Bioreactors
Blotting, Western
Cell Separation
Cell Survival--drug effects
Coculture Techniques
Cytochrome P-450 CYP2B1--metabolism
Cytochrome P-450 CYP3A
Female
Fibroblasts--drug effects
Hepatocytes--drug effects
Image Processing, Computer-Assisted
Liver--drug effects
Models, Statistical
Oxidoreductases, N-Demethylating--metabolism
Oxygen Consumption--physiology
Rats
Rats, Inbred Lew
Toxicity Tests