Pharmacological profile of CR3465, a new leukotriene CysLT1 receptor antagonist with broad anti-inflammatory activity. [electronic resource]
Producer: 20050930Description: 223-33 p. digitalISSN:- 0014-2999
- 3',5'-Cyclic-AMP Phosphodiesterases -- antagonists & inhibitors
- Animals
- Anti-Inflammatory Agents
- Bronchoalveolar Lavage Fluid -- cytology
- Bronchoconstriction -- drug effects
- Cell Degranulation -- drug effects
- Cyclic Nucleotide Phosphodiesterases, Type 3
- Cyclic Nucleotide Phosphodiesterases, Type 4
- Guinea Pigs
- Histamine -- pharmacology
- Histamine Antagonists -- pharmacology
- Humans
- In Vitro Techniques
- Leukotriene D4 -- antagonists & inhibitors
- Membrane Proteins -- antagonists & inhibitors
- N-Formylmethionine Leucyl-Phenylalanine -- pharmacology
- Neutrophils -- drug effects
- Parasympatholytics -- pharmacology
- Peroxidase -- metabolism
- Phosphodiesterase Inhibitors -- pharmacology
- Quinolines -- pharmacology
- Radioligand Assay
- Rats
- Receptors, Leukotriene
- Tumor Necrosis Factor-alpha -- metabolism
- Tyrosine -- analogs & derivatives
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Publication Type: Journal Article
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