Restoration of copper metabolism and rescue of hepatic abnormalities in LEC rats, an animal model of Wilson disease, by expression of human ATP7B gene. [electronic resource]
Producer: 20041209Description: 208-19 p. digitalISSN:- 0006-3002
- Adenosine Triphosphatases -- genetics
- Aging -- physiology
- Animals
- Animals, Genetically Modified
- Carcinoma, Hepatocellular -- genetics
- Cation Transport Proteins -- genetics
- Ceruloplasmin -- biosynthesis
- Copper -- metabolism
- Copper-Transporting ATPases
- Disease Models, Animal
- Female
- Gene Expression
- Hepatitis, Animal -- genetics
- Hepatolenticular Degeneration -- genetics
- Humans
- Iron -- metabolism
- Liver -- abnormalities
- Rats
- Rats, Inbred LEC
- Rats, Sprague-Dawley
- Survival Rate
- Transgenes -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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