Simvastatin induces proliferation inhibition and apoptosis in C6 glioma cells via c-jun N-terminal kinase. [electronic resource]
Producer: 20050131Description: 212-7 p. digitalISSN:- 0304-3940
- Activating Transcription Factor 2
- Animals
- Apoptosis -- drug effects
- Cell Line, Tumor -- cytology
- Cell Proliferation -- drug effects
- Cyclic AMP Response Element-Binding Protein -- metabolism
- DNA Fragmentation -- drug effects
- Glioma
- Hydroxymethylglutaryl-CoA Reductase Inhibitors -- pharmacology
- Immunohistochemistry -- methods
- JNK Mitogen-Activated Protein Kinases -- metabolism
- Mice
- Mitogen-Activated Protein Kinase 3 -- metabolism
- Phosphorylation -- drug effects
- Proliferating Cell Nuclear Antigen -- metabolism
- Protein Serine-Threonine Kinases -- metabolism
- Proto-Oncogene Proteins -- metabolism
- Proto-Oncogene Proteins c-akt
- Proto-Oncogene Proteins c-jun -- metabolism
- Simvastatin -- pharmacology
- Time Factors
- Transcription Factors -- metabolism
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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