Evidence that assembly of an active gamma-secretase complex occurs in the early compartments of the secretory pathway. [electronic resource]
Producer: 20050111Description: 48615-9 p. digitalISSN:- 0021-9258
- Amino Acid Motifs
- Amyloid Precursor Protein Secretases
- Amyloid beta-Protein Precursor -- chemistry
- Aspartic Acid Endopeptidases
- Benzophenones -- pharmacology
- Binding Sites
- Biotinylation
- Blotting, Western
- Catalysis
- Cell Line
- Cell Membrane -- metabolism
- Cell-Free System
- Cross-Linking Reagents -- pharmacology
- DNA, Complementary -- metabolism
- Endopeptidases -- chemistry
- Endoplasmic Reticulum -- metabolism
- Enzyme Inhibitors -- pharmacology
- Epitopes -- chemistry
- Golgi Apparatus -- metabolism
- Humans
- Membrane Proteins -- chemistry
- Peptide Hydrolases
- Protein Conformation
- Protein Structure, Tertiary
- Receptors, Notch
- Transfection
- trans-Golgi Network -- chemistry
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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