Evidence that assembly of an active gamma-secretase complex occurs in the early compartments of the secretory pathway.

Kim, Seong-Hun

Evidence that assembly of an active gamma-secretase complex occurs in the early compartments of the secretory pathway. [electronic resource] - The Journal of biological chemistry Nov 2004 - 48615-9 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0021-9258

10.1074/jbc.C400396200 doi


Amino Acid Motifs
Amyloid Precursor Protein Secretases
Amyloid beta-Protein Precursor--chemistry
Aspartic Acid Endopeptidases
Benzophenones--pharmacology
Binding Sites
Biotinylation
Blotting, Western
Catalysis
Cell Line
Cell Membrane--metabolism
Cell-Free System
Cross-Linking Reagents--pharmacology
DNA, Complementary--metabolism
Endopeptidases--chemistry
Endoplasmic Reticulum--metabolism
Enzyme Inhibitors--pharmacology
Epitopes--chemistry
Golgi Apparatus--metabolism
Humans
Membrane Proteins--chemistry
Peptide Hydrolases
Protein Conformation
Protein Structure, Tertiary
Receptors, Notch
Transfection
trans-Golgi Network--chemistry