A novel mechanism of FK506-mediated neuroprotection: downregulation of cytokine expression in glial cells. [electronic resource]
Producer: 20050321Description: 36-51 p. digitalISSN:- 0894-1491
- Animals
- Animals, Newborn
- Astrocytes -- drug effects
- Brain -- drug effects
- Cells, Cultured
- Cerebral Infarction -- drug therapy
- Cytokines -- genetics
- Disease Models, Animal
- Down-Regulation -- drug effects
- Gliosis -- drug therapy
- Immunosuppressive Agents -- pharmacology
- Infarction, Middle Cerebral Artery -- drug therapy
- Interleukin-1 -- genetics
- Interleukin-6 -- genetics
- Ischemic Attack, Transient -- drug therapy
- Lipopolysaccharides -- antagonists & inhibitors
- Male
- Microglia -- drug effects
- Neuroglia -- drug effects
- Neuroprotective Agents -- pharmacology
- RNA, Messenger -- drug effects
- Rats
- Rats, Wistar
- Reperfusion Injury -- drug therapy
- Tacrolimus -- pharmacology
- Tumor Necrosis Factor-alpha -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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