A novel mechanism of FK506-mediated neuroprotection: downregulation of cytokine expression in glial cells.

Zawadzka, Malgorzata

A novel mechanism of FK506-mediated neuroprotection: downregulation of cytokine expression in glial cells. [electronic resource] - Glia Jan 2005 - 36-51 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0894-1491

10.1002/glia.20092 doi


Animals
Animals, Newborn
Astrocytes--drug effects
Brain--drug effects
Cells, Cultured
Cerebral Infarction--drug therapy
Cytokines--genetics
Disease Models, Animal
Down-Regulation--drug effects
Gliosis--drug therapy
Immunosuppressive Agents--pharmacology
Infarction, Middle Cerebral Artery--drug therapy
Interleukin-1--genetics
Interleukin-6--genetics
Ischemic Attack, Transient--drug therapy
Lipopolysaccharides--antagonists & inhibitors
Male
Microglia--drug effects
Neuroglia--drug effects
Neuroprotective Agents--pharmacology
RNA, Messenger--drug effects
Rats
Rats, Wistar
Reperfusion Injury--drug therapy
Tacrolimus--pharmacology
Tumor Necrosis Factor-alpha--genetics