CHK1 and CHK2 are differentially involved in mismatch repair-mediated 6-thioguanine-induced cell cycle checkpoint responses. [electronic resource]
Producer: 20050209Description: 1147-57 p. digitalISSN:- 1535-7163
- Antimetabolites, Antineoplastic -- pharmacology
- Ataxia Telangiectasia Mutated Proteins
- Base Pair Mismatch
- Caffeine -- pharmacology
- Cell Cycle -- drug effects
- Cell Cycle Proteins -- genetics
- Cell Line, Tumor
- Checkpoint Kinase 1
- Checkpoint Kinase 2
- Colorectal Neoplasms -- metabolism
- DNA Repair -- genetics
- DNA-Binding Proteins
- Humans
- Phosphorylation
- Protein Kinases -- genetics
- Protein Serine-Threonine Kinases -- genetics
- RNA, Small Interfering -- genetics
- Staurosporine -- analogs & derivatives
- Thioguanine -- pharmacology
- Tumor Suppressor Proteins
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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