CHK1 and CHK2 are differentially involved in mismatch repair-mediated 6-thioguanine-induced cell cycle checkpoint responses.

Yan, Tao

CHK1 and CHK2 are differentially involved in mismatch repair-mediated 6-thioguanine-induced cell cycle checkpoint responses. [electronic resource] - Molecular cancer therapeutics Sep 2004 - 1147-57 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

1535-7163


Antimetabolites, Antineoplastic--pharmacology
Ataxia Telangiectasia Mutated Proteins
Base Pair Mismatch
Caffeine--pharmacology
Cell Cycle--drug effects
Cell Cycle Proteins--genetics
Cell Line, Tumor
Checkpoint Kinase 1
Checkpoint Kinase 2
Colorectal Neoplasms--metabolism
DNA Repair--genetics
DNA-Binding Proteins
Humans
Phosphorylation
Protein Kinases--genetics
Protein Serine-Threonine Kinases--genetics
RNA, Small Interfering--genetics
Staurosporine--analogs & derivatives
Thioguanine--pharmacology
Tumor Suppressor Proteins