Unique natural antioxidants (NAOs) and derived purified components inhibit cell cycle progression by downregulation of ppRb and E2F in human PC3 prostate cancer cells. [electronic resource]
Producer: 20041008Description: 31-7 p. digitalISSN:- 0014-5793
- Antioxidants -- pharmacology
- CDC2-CDC28 Kinases -- metabolism
- Cell Cycle -- drug effects
- Cell Cycle Proteins -- metabolism
- Cell Division -- drug effects
- Cell Line, Tumor
- Cell Survival -- drug effects
- Cyclin A -- metabolism
- Cyclin-Dependent Kinase 2
- Cyclin-Dependent Kinase Inhibitor p21
- Cyclins -- metabolism
- DNA-Binding Proteins -- metabolism
- Dose-Response Relationship, Drug
- Down-Regulation -- drug effects
- E2F Transcription Factors
- E2F1 Transcription Factor
- Flavonoids -- isolation & purification
- G1 Phase -- drug effects
- Humans
- Male
- Phenols -- isolation & purification
- Phosphorylation -- drug effects
- Plant Extracts -- chemistry
- Polyphenols
- Prostatic Neoplasms -- metabolism
- Retinoblastoma Protein -- metabolism
- S Phase -- drug effects
- Spinacia oleracea -- chemistry
- Transcription Factors -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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