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Bakshi, Shlomo

Unique natural antioxidants (NAOs) and derived purified components inhibit cell cycle progression by downregulation of ppRb and E2F in human PC3 prostate cancer cells. [electronic resource] - FEBS letters Aug 2004 - 31-7 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

ISSN: 0014-5793

Standard No.: 10.1016/j.febslet.2004.06.101 doi

Subjects--Topical Terms:
Antioxidants--pharmacology
CDC2-CDC28 Kinases--metabolism
Cell Cycle--drug effects
Cell Cycle Proteins--metabolism
Cell Division--drug effects
Cell Line, Tumor
Cell Survival--drug effects
Cyclin A--metabolism
Cyclin-Dependent Kinase 2
Cyclin-Dependent Kinase Inhibitor p21
Cyclins--metabolism
DNA-Binding Proteins--metabolism
Dose-Response Relationship, Drug
Down-Regulation--drug effects
E2F Transcription Factors
E2F1 Transcription Factor
Flavonoids--isolation & purification
G1 Phase--drug effects
Humans
Male
Phenols--isolation & purification
Phosphorylation--drug effects
Plant Extracts--chemistry
Polyphenols
Prostatic Neoplasms--metabolism
Retinoblastoma Protein--metabolism
S Phase--drug effects
Spinacia oleracea--chemistry
Transcription Factors--metabolism