SPRY2 is an inhibitor of the ras/extracellular signal-regulated kinase pathway in melanocytes and melanoma cells with wild-type BRAF but not with the V599E mutant. [electronic resource]
Producer: 20040930Description: 5556-9 p. digitalISSN:- 0008-5472
- Cell Line, Tumor
- Gene Expression Profiling
- Humans
- Intracellular Signaling Peptides and Proteins
- MAP Kinase Signaling System -- physiology
- Melanocytes -- enzymology
- Melanoma -- enzymology
- Membrane Proteins
- Mitogen-Activated Protein Kinases -- antagonists & inhibitors
- Mutation
- Oligonucleotide Array Sequence Analysis
- Protein Biosynthesis
- Proteins -- antagonists & inhibitors
- Proto-Oncogene Proteins B-raf
- Proto-Oncogene Proteins c-raf -- genetics
- RNA, Small Interfering -- genetics
- Transfection
- ras Proteins -- antagonists & inhibitors
No physical items for this record
Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
There are no comments on this title.
Log in to your account to post a comment.