Tamoxifen resistance by a conformational arrest of the estrogen receptor alpha after PKA activation in breast cancer. [electronic resource]
Producer: 20040719Description: 597-605 p. digitalISSN:- 1535-6108
- Antineoplastic Agents, Hormonal -- pharmacology
- Binding Sites
- Blotting, Western
- Breast Neoplasms -- enzymology
- Cell Division
- Cell Line, Tumor
- Cyclic AMP-Dependent Protein Kinases -- metabolism
- Down-Regulation
- Drug Resistance, Neoplasm
- Enzyme Activation
- Enzyme Inhibitors -- pharmacology
- Estradiol -- analogs & derivatives
- Estrogen Receptor Modulators -- pharmacology
- Estrogen Receptor alpha
- Female
- Fluorescence Resonance Energy Transfer
- Fulvestrant
- Humans
- Luciferases -- metabolism
- Microscopy, Confocal
- Models, Biological
- Nucleic Acid Hybridization
- Oligonucleotide Array Sequence Analysis
- Phosphorylation
- Protein Conformation
- Protein Structure, Tertiary
- RNA Interference
- Receptors, Estrogen -- chemistry
- Serine -- chemistry
- Tamoxifen -- pharmacology
- Time Factors
- Transcriptional Activation
- Transfection
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Publication Type: Journal Article
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