Molecular modelling of the nucleotide-binding domain of Wilson's disease protein: location of the ATP-binding site, domain dynamics and potential effects of the major disease mutations. [electronic resource]
Producer: 20050307Description: 293-305 p. digitalISSN:- 1470-8728
- Adenosine Triphosphatases -- chemistry
- Adenosine Triphosphate -- metabolism
- Amino Acid Sequence -- genetics
- Binding Sites
- Calcium-Transporting ATPases -- metabolism
- Cation Transport Proteins -- chemistry
- Circular Dichroism -- methods
- Computer Simulation
- Copper-Transporting ATPases
- Hepatolenticular Degeneration -- genetics
- Models, Molecular
- Models, Structural
- Molecular Sequence Data
- Mutagenesis -- genetics
- Mutation -- genetics
- Nucleotides -- metabolism
- Peptides -- chemistry
- Protein Binding
- Protein Structure, Tertiary
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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