The histone deacetylase inhibitor MS-275 induces caspase-dependent apoptosis in B-cell chronic lymphocytic leukemia cells. [electronic resource]
Producer: 20040723Description: 1207-14 p. digitalISSN:- 0887-6924
- Apoptosis -- drug effects
- Benzamides -- pharmacology
- CASP8 and FADD-Like Apoptosis Regulating Protein
- Carrier Proteins -- metabolism
- Caspases -- metabolism
- Enzyme Inhibitors -- pharmacology
- Histone Deacetylase Inhibitors
- Humans
- Intracellular Signaling Peptides and Proteins
- Leukemia, Lymphocytic, Chronic, B-Cell -- drug therapy
- Leukocytes, Mononuclear -- drug effects
- Proto-Oncogene Proteins c-bcl-2 -- physiology
- Pyridines -- pharmacology
- Reactive Oxygen Species -- metabolism
- Tumor Cells, Cultured
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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