The histone deacetylase inhibitor MS-275 induces caspase-dependent apoptosis in B-cell chronic lymphocytic leukemia cells.
Lucas, D M
The histone deacetylase inhibitor MS-275 induces caspase-dependent apoptosis in B-cell chronic lymphocytic leukemia cells. [electronic resource] - Leukemia Jul 2004 - 1207-14 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0887-6924
10.1038/sj.leu.2403388 doi
Apoptosis--drug effects
Benzamides--pharmacology
CASP8 and FADD-Like Apoptosis Regulating Protein
Carrier Proteins--metabolism
Caspases--metabolism
Enzyme Inhibitors--pharmacology
Histone Deacetylase Inhibitors
Humans
Intracellular Signaling Peptides and Proteins
Leukemia, Lymphocytic, Chronic, B-Cell--drug therapy
Leukocytes, Mononuclear--drug effects
Proto-Oncogene Proteins c-bcl-2--physiology
Pyridines--pharmacology
Reactive Oxygen Species--metabolism
Tumor Cells, Cultured
The histone deacetylase inhibitor MS-275 induces caspase-dependent apoptosis in B-cell chronic lymphocytic leukemia cells. [electronic resource] - Leukemia Jul 2004 - 1207-14 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0887-6924
10.1038/sj.leu.2403388 doi
Apoptosis--drug effects
Benzamides--pharmacology
CASP8 and FADD-Like Apoptosis Regulating Protein
Carrier Proteins--metabolism
Caspases--metabolism
Enzyme Inhibitors--pharmacology
Histone Deacetylase Inhibitors
Humans
Intracellular Signaling Peptides and Proteins
Leukemia, Lymphocytic, Chronic, B-Cell--drug therapy
Leukocytes, Mononuclear--drug effects
Proto-Oncogene Proteins c-bcl-2--physiology
Pyridines--pharmacology
Reactive Oxygen Species--metabolism
Tumor Cells, Cultured