Discovery of novel 2,8-diazaspiro[4.5]decanes as orally active glycoprotein IIb-IIIa antagonists. [electronic resource]
Producer: 20040519Description: 2037-61 p. digitalISSN:- 0022-2623
- Administration, Oral
- Alkanes -- chemical synthesis
- Animals
- Aza Compounds -- chemical synthesis
- Binding, Competitive
- Biological Availability
- Bleeding Time
- Dogs
- Humans
- Hydantoins -- chemical synthesis
- Hydroxylamines -- chemical synthesis
- In Vitro Techniques
- Lactams -- chemical synthesis
- Macaca fascicularis
- Mice
- Platelet Aggregation Inhibitors -- chemical synthesis
- Platelet Glycoprotein GPIIb-IIIa Complex -- antagonists & inhibitors
- Prodrugs -- chemical synthesis
- Rats
- Rats, Sprague-Dawley
- Spiro Compounds -- chemical synthesis
- Structure-Activity Relationship
- Urea -- analogs & derivatives
No physical items for this record
Publication Type: Journal Article
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