Evidence for a local angiotensin-generating system and dose-dependent inhibition of glucose-stimulated insulin release by angiotensin II in isolated pancreatic islets. [electronic resource]
Producer: 20050114Description: 240-8 p. digitalISSN:- 0012-186X
- Angiotensin II -- pharmacology
- Angiotensin II Type 1 Receptor Blockers
- Angiotensin II Type 2 Receptor Blockers
- Angiotensinogen -- genetics
- Animals
- Blotting, Western
- Dose-Response Relationship, Drug
- Gene Expression -- drug effects
- Glucose -- metabolism
- Imidazoles -- pharmacology
- Immunohistochemistry
- In Vitro Techniques
- Insulin -- metabolism
- Insulin Secretion
- Islets of Langerhans -- drug effects
- Islets of Langerhans Transplantation -- methods
- Losartan -- pharmacology
- Male
- Mice
- Mice, Inbred C57BL
- Oxidation-Reduction -- drug effects
- Peptidyl-Dipeptidase A -- genetics
- Proinsulin -- biosynthesis
- Protein Biosynthesis
- Pyridines -- pharmacology
- Receptor, Angiotensin, Type 1 -- genetics
- Receptor, Angiotensin, Type 2 -- genetics
- Renin-Angiotensin System -- genetics
- Reverse Transcriptase Polymerase Chain Reaction
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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