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Lau, T

Evidence for a local angiotensin-generating system and dose-dependent inhibition of glucose-stimulated insulin release by angiotensin II in isolated pancreatic islets. [electronic resource] - Diabetologia Feb 2004 - 240-8 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

ISSN: 0012-186X

Standard No.: 10.1007/s00125-003-1295-1 doi

Subjects--Topical Terms:
Angiotensin II--pharmacology
Angiotensin II Type 1 Receptor Blockers
Angiotensin II Type 2 Receptor Blockers
Angiotensinogen--genetics
Animals
Blotting, Western
Dose-Response Relationship, Drug
Gene Expression--drug effects
Glucose--metabolism
Imidazoles--pharmacology
Immunohistochemistry
In Vitro Techniques
Insulin--metabolism
Insulin Secretion
Islets of Langerhans--drug effects
Islets of Langerhans Transplantation--methods
Losartan--pharmacology
Male
Mice
Mice, Inbred C57BL
Oxidation-Reduction--drug effects
Peptidyl-Dipeptidase A--genetics
Proinsulin--biosynthesis
Protein Biosynthesis
Pyridines--pharmacology
Receptor, Angiotensin, Type 1--genetics
Receptor, Angiotensin, Type 2--genetics
Renin-Angiotensin System--genetics
Reverse Transcriptase Polymerase Chain Reaction