SREBP-1 interacts with hepatocyte nuclear factor-4 alpha and interferes with PGC-1 recruitment to suppress hepatic gluconeogenic genes. [electronic resource]
Producer: 20040507Description: 12027-35 p. digitalISSN:- 0021-9258
- Animals
- Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
- Binding Sites
- Binding, Competitive
- Blotting, Northern
- CCAAT-Enhancer-Binding Proteins -- metabolism
- Cell Line
- Colforsin -- pharmacology
- DNA-Binding Proteins -- metabolism
- Dose-Response Relationship, Drug
- Gene Expression Regulation
- Glutathione Transferase -- metabolism
- Hepatocyte Nuclear Factor 4
- Humans
- Ligands
- Lipoproteins, LDL -- metabolism
- Liver -- metabolism
- Luciferases -- metabolism
- Mice
- Mice, Transgenic
- Models, Genetic
- Phosphoenolpyruvate Carboxykinase (GTP) -- biosynthesis
- Phosphoproteins -- metabolism
- Plasmids -- metabolism
- Precipitin Tests
- Promoter Regions, Genetic
- Protein Binding
- Protein Isoforms
- Protein Structure, Tertiary
- RNA -- metabolism
- Recombinant Fusion Proteins -- metabolism
- Sterol Regulatory Element Binding Protein 1
- Sterol Regulatory Element Binding Protein 2
- Transcription Factors -- metabolism
- Transcription, Genetic
- Transcriptional Activation
- Transfection
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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