SREBP-1 interacts with hepatocyte nuclear factor-4 alpha and interferes with PGC-1 recruitment to suppress hepatic gluconeogenic genes.

Yamamoto, Takashi

SREBP-1 interacts with hepatocyte nuclear factor-4 alpha and interferes with PGC-1 recruitment to suppress hepatic gluconeogenic genes. [electronic resource] - The Journal of biological chemistry Mar 2004 - 12027-35 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0021-9258

10.1074/jbc.M310333200 doi


Animals
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
Binding Sites
Binding, Competitive
Blotting, Northern
CCAAT-Enhancer-Binding Proteins--metabolism
Cell Line
Colforsin--pharmacology
DNA-Binding Proteins--metabolism
Dose-Response Relationship, Drug
Gene Expression Regulation
Glutathione Transferase--metabolism
Hepatocyte Nuclear Factor 4
Humans
Ligands
Lipoproteins, LDL--metabolism
Liver--metabolism
Luciferases--metabolism
Mice
Mice, Transgenic
Models, Genetic
Phosphoenolpyruvate Carboxykinase (GTP)--biosynthesis
Phosphoproteins--metabolism
Plasmids--metabolism
Precipitin Tests
Promoter Regions, Genetic
Protein Binding
Protein Isoforms
Protein Structure, Tertiary
RNA--metabolism
Recombinant Fusion Proteins--metabolism
Sterol Regulatory Element Binding Protein 1
Sterol Regulatory Element Binding Protein 2
Transcription Factors--metabolism
Transcription, Genetic
Transcriptional Activation
Transfection